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dnanexus-integration

dnanexus-integration

42Ksecurity

Build and operate reproducible genomics workloads on DNAnexus with the dx CLI, dxpy, apps/applets, native workflows, dxCompiler, and Nextflow. Use for DNAnexus data transfers, dxapp.json development, execution monitoring, workflow import, and project automation.

k-dense-ai avatark-dense-ai
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polars-bio

polars-bio

42Kresearch-knowledge

High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap, nearest, merge, coverage, complement, subtract for BED/VCF/BAM/GFF intervals. Streaming, cloud-native, faster bioframe alternative.

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primekg

primekg

42Kresearch-knowledge

Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological data including genes, drugs, diseases, phenotypes, and more.

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latchbio-integration

latchbio-integration

42Kresearch-knowledge

Build, register, debug, and operate bioinformatics workflows on Latch using the Python SDK, CLI, Latch Data and Registry, Nextflow, Snakemake, programmatic execution, and Latch MCP. Use when authoring or deploying Latch workflows, configuring resources or interfaces, moving data, integrating Registry, or launching and monitoring runs.

k-dense-ai avatark-dense-ai
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omero-integration

omero-integration

42Kresearch-knowledge

Securely inspect and automate microscopy data workflows against OMERO.server with omero-py, BlitzGateway, OMERO CLI, tables, annotations, ROIs, rendering, and documented OMERO.web APIs. Use for scoped OMERO inventory, metadata export, import/export planning, or reviewed write workflows.

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glycoengineering

glycoengineering

42Kresearch-knowledge

Analyze and engineer protein glycosylation. Scan sequences for N-glycosylation sequons (N-X-S/T), predict O-glycosylation hotspots, and access curated glycoengineering tools (NetOGlyc, GlycoShield, GlycoWorkbench). For glycoprotein engineering, therapeutic antibody optimization, and vaccine design.

k-dense-ai avatark-dense-ai
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ginkgo-cloud-lab

ginkgo-cloud-lab

42Kagent-workflows

Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and ordering workflows.

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paperzilla

paperzilla

42Kresearch-knowledge

Chat with your agent about projects, recommendations, and canonical papers in Paperzilla. Use when users ask for recent project recommendations, canonical paper details, markdown-based summaries, recommendation feedback, feed export, or Atom feed URLs.

k-dense-ai avatark-dense-ai
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influencer-marketing

influencer-marketing

42Kmarketing-seo

当用户希望开展网红、创作者或品牌大使合作来推广产品时使用——包括寻找和筛选合作伙伴、构建合作方案、向创作者提供简报、合规披露以及衡量投资回报率。当用户提及以下关键词时也适用:'网红营销'、'创作者合作'、'赞助'、'YouTube赞助'、'播客赞助'、'品牌大使'、'大使计划'、'创作者计划'、'UGC创作者'、'B2B网红'、'意见领袖广告'、'赠送'、'产品试用'、'白名单创作者内容'、'给网红付多少钱'或'FTC披露'。关于联盟/推荐佣金机制,请参考referrals。关于社区驱动的倡导,请参考community-marketing。关于将创作者内容转化为付费广告,请参考ad-creative。

coreyhaines31 avatarcoreyhaines31
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nodejs-best-practices

nodejs-best-practices

42Ktesting-qa

Node.js 开发原则与决策。框架选择、异步模式、安全性和架构。教授思考方法,而非复制代码。

sickn33 avatarsickn33
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research-lookup

research-lookup

42Kresearch-knowledge

Compile current scholarly evidence for a scientific manuscript or research brief. Use when the user explicitly asks to gather literature, references, background evidence, competing findings, or a manuscript research packet. Uses Parallel Search by default, Parallel Extract for source verification, Parallel Research for explicitly deep/exhaustive work, optional explicit Parallel Chat, and optional Perplexity only when requested or allowed as a failure fallback.

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clinical-decision-support

clinical-decision-support

42Kresearch-knowledge

Prepare and validate research-only clinical decision-support evaluation, evidence-profile, cohort, survival, biomarker/model, privacy, and governance artifacts. Use for aggregate or synthetic research documentation and traceability—not patient care or live clinical operation.

k-dense-ai avatark-dense-ai
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pydicom

pydicom

42Kresearch-knowledge

Use pydicom to read, inspect, write, transform, and safely preflight local DICOM datasets and pixel data. Applies to DICOM metadata, transfer syntaxes, compression plugins, frames, private elements, JSON, and bounded de-identification review.

k-dense-ai avatark-dense-ai
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vaex

vaex

42Kresearch-knowledge

Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that do not fit in memory.

k-dense-ai avatark-dense-ai
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modal

modal

42Kbackend-api

Modal is a serverless cloud platform for running Python on demand, including on-demand GPUs. Use when deploying or serving AI/ML models, running GPU-accelerated workloads (training, fine-tuning, inference), serving web endpoints, scheduling batch jobs, or scaling Python code to cloud containers with the Modal SDK.

k-dense-ai avatark-dense-ai
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pufferlib

pufferlib

42Kresearch-knowledge

Version-aware guidance for PufferLib reinforcement-learning environments, vectorization, policies, PuffeRL training, evaluation, and safe checkpoint review. Use when adapting Gymnasium/PettingZoo environments to published PufferLib 3.0.0 or working with the redesigned native 4.0 source line.

k-dense-ai avatark-dense-ai
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scanpy

scanpy

42Kresearch-knowledge

Standard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction (PCA/UMAP/t-SNE), clustering, differential expression, visualization, and converting R-friendly single-cell formats such as Seurat or SingleCellExperiment RDS files into h5ad for Scanpy. Best for exploratory scRNA-seq analysis with established workflows. For deep learning models use scvi-tools; for data format questions use anndata.

k-dense-ai avatark-dense-ai
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deeptools

deeptools

42Kresearch-knowledge

NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.

k-dense-ai avatark-dense-ai
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rdkit

rdkit

42Kresearch-knowledge

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.

k-dense-ai avatark-dense-ai
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benchling-integration

benchling-integration

42Kresearch-knowledge

Benchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries. Use when automating lab data with benchling-sdk or the v2 API.

k-dense-ai avatark-dense-ai
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deepchem

deepchem

42Kresearch-knowledge

Molecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity) with traditional ML or GNNs when you want extensive featurization options and MoleculeNet benchmarks. Best for quick experiments with pre-trained models, diverse molecular representations. For graph-first PyTorch workflows use torchdrug; for benchmark datasets use pytdc.

k-dense-ai avatark-dense-ai
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pyhealth

pyhealth

42Kresearch-knowledge

Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep staging, ICD coding, EEG events), instantiating models (Transformer, RETAIN, GAMENet, SafeDrug, MICRON, StageNet, AdaCare, CNN/RNN/MLP), training with the PyHealth Trainer, computing clinical metrics, and using medical code utilities (ICD/ATC/NDC/RxNorm lookup and cross-mapping). Use this skill whenever the user mentions PyHealth, MIMIC, eICU, OMOP, EHR modeling, clinical prediction, drug recommendation, sleep staging, medical code mapping, ICD/ATC codes, or any healthcare ML pipeline that fits the dataset → task → model → trainer → metrics pattern, even if "PyHealth" isn't named explicitly.

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pydeseq2

pydeseq2

42Kresearch-knowledge

Differential gene expression analysis for bulk RNA-seq with PyDESeq2, including formulaic designs, Wald tests, FDR correction, LFC shrinkage, and result visualization.

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imaging-data-commons

imaging-data-commons

42Kresearch-knowledge

Query and download public cancer imaging data from NCI Imaging Data Commons. Invoke for any question about IDC collections, cancer imaging datasets, DICOM data access, radiology (CT, MR, PET) or pathology AI training sets, metadata queries, visualization, or license checks — even when the user doesn't explicitly mention "IDC". No authentication required.

k-dense-ai avatark-dense-ai
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